When preparing for an exam, it is essential to familiarize yourself with the exam format, and Step 2 CK is no different. This exam aims to test an applicant’s clinical knowledge and how they can apply that knowledge in patient care. Step 2 CK is one part of the USMLE exam that judges how devoted an applicant is to the principles of clinical sciences and basic patient-centred skills, skills which provide the foundation for the safe and competent practice of medicine in the US, Canada and other countries where USMLE certification is recognized.
USMLE Step 2 CK is a one-day examination administered over the course of nine hours. The exam is divided into eight 60-minute blocks, and while the number of questions in each block may vary, it will not exceed 40. These questions stem from a very rich syllabus consisting of various subjects. This article provides a detailed breakdown of each subject and contains information on how to plan effectively for each one.
Step 2 CK Syllabus Overview
Step 2 CK assesses an applicant’s ability to apply the knowledge and skills they acquired in medical school and how they can apply them in real-life clinical scenarios. However, the exam itself is far from simple, in part because of how much information you’re expected to know. This information is divided across body systems, and this article provides a detailed breakdown.
Body Systems
The USMLE Step 2 CK tests an examinee’s knowledge of the body systems. However, knowledge of all systems is not tested equally, as some systems are known to produce more high-yield questions. Here’s a detailed breakdown of the systems tested on and the percentage of the exam allocated to each one.
- Human Development 2–4%
For this section, you are expected to know the age gap for infancy, childhood, adolescence, adulthood, and older adulthood. You should also be able to tell what occurrences are physiologic for each age bracket and which ones are pathogenic.
- Immune System 3–5%
This is a broad topic that contains a number of high-yield topics. You are expected to know the breakdown of the immune system and the specific functions of each part. You should also be able to tell B and T lymphocytes apart, from their patterns of development down to their functions. Know the complications that can arise from immune deficiency as well as immune hypersensitivity, and don’t forget to relate all these to clinical scenarios.
- Blood & Lymphoreticular System 4–6%
This is yet another important part of the Step 2 CK exam. You are expected to know the different components of blood, their respective functions, blood types, the different systems of blood grouping, and transfusion reactions. You should be able to interpret lab results, compare lab values with physiologic values, give a diagnosis and a course of treatment. You should be familiar with illnesses such as thalassemia, anemia, vitamin deficiencies, bleeding disorders, sickle cell anemia, leukemias, lymphomas, etc.
- Behavioral Health 6–8%
Questions from this course are typically the most straightforward. You are expected to know the DSM-5 criteria for psychological disorders, e.g. depression, bipolar disorder, anxiety, mania, schizophrenia, etc. You should also know the drugs used for each disorder and their mechanisms of action.
- Nervous System & Special Senses 6–8%
By the standards of this category, you are expected to be able to perform standard neurology exams, and have a good knowledge of stroke presentations, workup, and management. You should also be familiar with amnesia, vertigo, back pain, etc.
- Musculoskeletal System/Skin & Subcutaneous Tissue 6–10%
This section of the exam demands that you know the different presentations of skin melanomas and the clinical manifestations of several rashes – the ones that are allergic reactions or those that indicate organ damage. For the musculoskeletal system, you should know the different kinds of joint dislocations, fractures, and what vessels are at risk of being affected.
- Cardiovascular System 8–10%
The CVS is one of the most tested subjects in Step 2 CK, and one of the most talked about in medicine generally. You have to know about arrhythmias, congestive heart failure, hypertension, coronary artery disease, ischemic heart disease, and myocardial infarction. Don’t forget the risk factors for each of these diseases, their clinical manifestations, and management plans.
- Respiratory System 7–9%
The respiratory system has a lot of high-yield topics, but one of the most common ones is lung cancer. You are expected to have a good knowledge of the workup of a lung nodule, screening guidelines, the differences between the types of lung cancer, and what part of the population is at risk for which kind of cancer. Other high-yield topics are pleural effusion, pulmonary embolism, COPD, asthma, etc.
- Gastrointestinal System 7–9%
This is one of the most bulky systems that you will be tested on. You should be familiar with medical and surgical diseases of the GI system. From the esophagus all the way to the colon, and all the accessory organs in between – liver, spleen, gallbladder, pancreas – you should know the similarities and differences between diseases of these organs. Remember to take note of how each disease is tested.
- Renal & Urinary System & Male Reproductive 4–6%
The anatomy and physiology of the renal system are typically tested at the Step 2 CK exam. The examiner wants to know that you’re familiar with the several electrolyte imbalance diseases, as well as their indications and implications. Knowledge of the pathology of the nephron, kidney, and other organs in the urinary tract is also very important.
- Pregnancy, Childbirth & the Puerperium 4–6%
This section expects you to be able to differentiate between the physiologic and pathologic occurrences of pregnancy. You should be able to do pelvic exams and be familiar with the stages of labour, complications of childbirth, and the basics of how a C-Section is performed.
- Female Reproductive System & Breast 4–6%
This section is basically gynecology, and it tests your knowledge of the pathology of the female reproductive tract and the management of these diseases. You should know the basics of a breast exam and a pelvic exam, the tests for and manifestations of diseases like pelvic inflammatory disease, amenorrhea, PCOS, endometriosis, ovarian, cervical, and vaginal cancers, etcetera, etcetera.
- Endocrine System 4–6%
This is one of the best places to earn easy points. Be familiar with several endocrine disorders, the stimulants and inhibitors of the major hormones of the body, the functions of these hormones, and the tests for the abnormal functioning of these hormones.
- Multisystem Processes & Disorders 4–6%
This section is not easy to predict, but the general idea is to know of diseases that can affect multiple organ systems. Because of how unpredictable it is, dedicating too much study time to this particular category is not a smart idea.
- Biostatistics & Epidemiology/Population Health/Interpretation of Medical Literature 3–5%
This category tests your ability to interpret pictorial data and statistics. For calculations, practice over and over so you can easily recall important formulas.
- Social Sciences: Legal/Ethical Issues & Professionalism/Systems-based Practice & Patient Safety 10-15%
Questions from this category of the syllabus are straightforward, and all you need to know is clearly stated in the Step 2 CK topic breakdown.
Conclusion
Getting familiar with the course outline is a good way to kickstart your preparation for Step 2 CK, but there’s still more work to be done. Ensure you create an effective study schedule, practice past questions, and ask for help when you need it. Remember that CanadaQBank has a lot of resources that can make your studying easier.